Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage
Plasma cells (PC) or Ig-secreting cells (ISC) are terminally differentiated B cells responsible for the production of protective Ig. ISC can be generated in vitro by culturing human B cells with the T cell-derived stimuli CD40L, IL-2, and IL-10. ISC have
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|Source:||Journal of Immunology|
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