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The Evolution of Genomic Imprinting and X Chromosome Inactivation in Mammals

Hore, Tim


Genomic imprinting is responsible for monoallelic gene expression that depends on the sex of the parent from which the alleles (one active, one silent) were inherited. X-chromosome inactivation is also a form of monoallelic gene expression. One of the two X chromosomes is transcriptionally silenced in the somatic cells of females, effectively equalising gene dosage with males who have only one X chromosome that is not complemented by a gene poor Y chromosome. X chromosome inactivation is random...[Show more]

CollectionsOpen Access Theses
Date published: 2008-08
Type: Thesis (PhD)


File Description SizeFormat Image
10appendix.pdf1.52 MBAdobe PDFThumbnail
09references.pdf850.22 kBAdobe PDFThumbnail
08chapter6.pdf778.01 kBAdobe PDFThumbnail
07chapter5supp.pdf3.89 MBAdobe PDFThumbnail
06chapter5.pdf1.02 MBAdobe PDFThumbnail
05chapter4.pdf121.61 kBAdobe PDFThumbnail
04chapter3.pdf130.61 kBAdobe PDFThumbnail
03chapter2.pdf1.78 MBAdobe PDFThumbnail
02chapter1.pdf1.47 MBAdobe PDFThumbnail
01front.pdf441.59 kBAdobe PDFThumbnail

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