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The Role of Eosinophils in the Regulation of CD4+ T helper 2 Regulated Inflammation

MacKenzie, Jason Roderick


The eosinophil is a leukocyte whose intracellular mediators are considered to play a central role in the pathogenesis of allergic diseases, including allergic asthma, allergic rhinitis and atopic dermatitis, and which is also involved in immunological responses to parasites. Eosinophil differentiation and maturation from bone marrow progenitors is regulated by interleukin-5 (IL-5), which may be secreted by T helper 2 (Th2) T lymphocytes, and is consistently upregulated in allergic conditions....[Show more]

CollectionsOpen Access Theses
Date published: 2003
Type: Thesis (PhD)


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