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Stereoselective intramolecular Michael addition reactions of pyrrole and their application to natural product syntheses

Beck, Daniel Antony Speedie


Chapter one; “(-)-Rhazinilam and (-)-Rhazinal: Alkaloids with Anti-mitotic Properties Derived from Kopsia teoi”, provides the background information behind the motives that initiated this research project. The plant alkaloid (-)-rhazinilam [(-)-1] and its naturally-occurring derivative (-)-rhazinal [(-)-13] both exhibit potent anti-mitotic activities and, as such, are interesting targets for total synthesis. Chapter one is a review of the literature regarding these two compounds and discusses...[Show more]

CollectionsOpen Access Theses
Date published: 2006-02
Type: Thesis (PhD)


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02whole.pdf5.28 MBAdobe PDFThumbnail

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