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Does extreme prematurity affect kidney volume at term corrected age?

Kent, Alison; Jyoti, Rajeev; Robertson, Cameron; Gonsalves, Lisa; Meksell, Sandra; Shadbolt, Bruce; Falk, Michael C

Description

Objective. Extreme prematurity exposes the neonate to a number of potential renal insults that may result in a reduced number of glomeruli andor renal size. This may predispose these individuals to cardiovascular disease later in life. The objective was to determine using magnetic resonance imaging MRI whether extreme prematurity results in decreased renal volume. Methods. Neonates <29 weeks' gestation and term infants undergoing MRI of the brain were enrolled in the study. An MRI was performed...[Show more]

dc.contributor.authorKent, Alison
dc.contributor.authorJyoti, Rajeev
dc.contributor.authorRobertson, Cameron
dc.contributor.authorGonsalves, Lisa
dc.contributor.authorMeksell, Sandra
dc.contributor.authorShadbolt, Bruce
dc.contributor.authorFalk, Michael C
dc.date.accessioned2015-12-10T21:57:26Z
dc.identifier.issn1476-7058
dc.identifier.urihttp://hdl.handle.net/1885/39776
dc.description.abstractObjective. Extreme prematurity exposes the neonate to a number of potential renal insults that may result in a reduced number of glomeruli andor renal size. This may predispose these individuals to cardiovascular disease later in life. The objective was to determine using magnetic resonance imaging MRI whether extreme prematurity results in decreased renal volume. Methods. Neonates <29 weeks' gestation and term infants undergoing MRI of the brain were enrolled in the study. An MRI was performed at term corrected age in the premature neonate and within the first 4 weeks of life in the term neonate. Results. Seventeen preterm infants and 13 term infants had MRIs performed. There was no significant difference in weight and length at the time of MRI p 0.76 and 0.11, respectively. There was no significant difference in total renal volume or total kidney volume to weight ratio between the preterm and term neonates p 0.83 and 0.6, respectively. Conclusions. At term corrected age, extremely premature neonates have the same renal volume as term infants. It is unclear whether renal volume is a good indicator of glomerular number.
dc.publisherTaylor & Francis Group
dc.sourceJournal of Maternal - Fetal & Neonatal Medicine, The
dc.subjectKeywords: article; clinical article; controlled study; extremely low birth weight; female; gestational age; human; infant; kidney; male; neuroimaging; newborn; nuclear magnetic resonance imaging; prematurity; priority journal Birth weight; Extreme prematurity; MRI; Neonate; Renal volume
dc.titleDoes extreme prematurity affect kidney volume at term corrected age?
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume22
dc.date.issued2009
local.identifier.absfor111403 - Paediatrics
local.identifier.ariespublicationu4241283xPUB183
local.type.statusPublished Version
local.contributor.affiliationKent, Alison, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationJyoti, Rajeev, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationRobertson, Cameron, The Canberra Hospital
local.contributor.affiliationGonsalves, Lisa, The Canberra Hospital
local.contributor.affiliationMeksell, Sandra, The Canberra Hospital
local.contributor.affiliationShadbolt, Bruce, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationFalk, Michael C, Canberra Hospital
local.description.embargo2037-12-31
local.bibliographicCitation.issue5
local.bibliographicCitation.startpage435
local.bibliographicCitation.lastpage438
local.identifier.doi10.1080/14767050802692102
dc.date.updated2016-02-24T10:47:20Z
local.identifier.scopusID2-s2.0-69149089895
CollectionsANU Research Publications

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