Improving Clinical Outcomes in Treating Heroine Dependence :Randomised Controlled Trial of Oral or Implant Naltrexone
Context: Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance. Sustained-release preparations may overcome this limitation. Objective: To compare the safety and efficacy of a single-treatment sustained-release naltrexone implant with daily oral naltrexone treatment. Design: Seventy heroin-dependent volunteers entered a randomized, double-blind, double-placebo controlled trial with a 6-month follow-up period. Patients: Eligibility...[Show more]
|Collections||ANU Research Publications|
|Source:||Archives of General Psychiatry|
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