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Improving Clinical Outcomes in Treating Heroine Dependence :Randomised Controlled Trial of Oral or Implant Naltrexone

Hulse, Gary; Morris, Noella; Arnold-Reed, Diane; Tait, Robert

Description

Context: Oral naltrexone hydrochloride effectively antagonizes heroin, but its utility is limited by patient noncompliance. Sustained-release preparations may overcome this limitation. Objective: To compare the safety and efficacy of a single-treatment sustained-release naltrexone implant with daily oral naltrexone treatment. Design: Seventy heroin-dependent volunteers entered a randomized, double-blind, double-placebo controlled trial with a 6-month follow-up period. Patients: Eligibility...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/39774
Source: Archives of General Psychiatry
DOI: 10.1001/archgenpsychiatry.2009.130

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