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Targeting tumour cells at the entrance

Broer, Stefan

Description

Metabolism in tumour cells is adapted to the demands of a growing cell. The Warburg effect and increased use of glutamine are two well-known adaptations of tumour metabolism. Both require transporters to allow uptake of substrates and efflux of products.

dc.contributor.authorBroer, Stefan
dc.date.accessioned2015-12-10T21:56:44Z
dc.identifier.issn0264-6021
dc.identifier.urihttp://hdl.handle.net/1885/39572
dc.description.abstractMetabolism in tumour cells is adapted to the demands of a growing cell. The Warburg effect and increased use of glutamine are two well-known adaptations of tumour metabolism. Both require transporters to allow uptake of substrates and efflux of products.
dc.publisherPortland Press
dc.sourceBiochemical Journal
dc.subjectKeywords: fingolimod; sphingosine 1 phosphate; sphingosine kinase; cancer inhibition; cell metabolism; nonhuman; note; nutrient uptake; priority journal; tumor cell; Warburg effect; Animals; Carrier Proteins; Down-Regulation; Sphingolipids Glutaminolysis; Leukaemia; Nutrient limitation; Sphingosine 1-phosphate; Transporter; Warburg effect
dc.titleTargeting tumour cells at the entrance
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume439
dc.date.issued2011
local.identifier.absfor060110 - Receptors and Membrane Biology
local.identifier.ariespublicationu8611701xPUB179
local.type.statusPublished Version
local.contributor.affiliationBroer, Stefan, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpagee1
local.bibliographicCitation.lastpagee2
local.identifier.doi10.1042/BJ20111484
local.identifier.absseo920110 - Inherited Diseases (incl. Gene Therapy)
dc.date.updated2016-02-24T11:41:23Z
local.identifier.scopusID2-s2.0-80053291840
CollectionsANU Research Publications

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