Skip navigation
Skip navigation

Terminal Deoxynucleotidyl Transferase Establishes andBroadens Antiviral CD8+ T Cell Immunodominance Hierarchies1

Haeryfar, S M Mansour; Hickman, Heather D.; Irvine, Kari R; Tscharke, David; Bennink, Jack R; Yewdell, Jonathan W


The action of TdT on mouse TCR genes accounts for ∼90% of T cell repertoire diversity. We report that in TdT -/- mice, total T CD8+ responses to influenza and vaccinia viruses are reduced by ∼30% relative to wild-type mice. We find that T CD8+ respons

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Immunology


File Description SizeFormat Image
01_Haeryfar_Terminal_Deoxynucleotidyl_2008.pdf659.54 kBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator