Combining data from 2 nested case-control studies of overlapping cohorts to improve efficiency
Researchers subject to time and budget constraints may conduct small nested case-control studies with individually matched controls to help optimize statistical power. In this paper, we show how precision can be improved considerably by combining data from a small nested case-control study with data from a larger nested case-control study of a different outcome in the same or overlapping cohort. Our approach is based on the inverse probability weighting concept, in which the log-likelihood...[Show more]
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