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No association between the serotonin-1A receptor gene single nucleotide polymorphism rs6295C/G and symptoms of anxiety or depression, and no interaction between the polymorphism and environmental stressors of childhood anxiety or recent stressful life events on anxiety or depression

Chipman, Phillip; Jorm, Anthony F; Tan, Susan (Xiaoyun); Easteal, Simon


Background: There are conflicting reports of an association between a common functional single nucleotide polymorphism (rs6295C/G) in the serotonin-1A receptor gene (HTR1A) and psychological disorders. Methods: In our study we investigated associations between this polymorphism and symptoms of anxiety and depression in a population sample of 6445 Caucasians in the age groups 20-24, 40-44, and 60-64 years. We also looked for interactions between the polymorphism and environmental stressors of...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Psychiatric Genetics
DOI: 10.1097/YPG.0b013e3283351140


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