Apical Transporters for Neutral Amino acids: Physiology and Pathophysiology
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Absorption of amino acids in kidney and intestine involves a variety of transporters for different groups of amino acids. This is illustrated by inherited disorders of amino acid absorption, such as Hartnup disorder, cystinuria, iminoglycinuria, dicarboxylic aminoaciduria, and lysinuric protein intolerance, affecting separate groups of amino acids. Recent advances in the molecular identification of apical neutral amino acid transporters has shed a light on the molecular basis of Hartnup...[Show more]
dc.contributor.author | Broer, Stefan | |
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dc.date.accessioned | 2015-12-10T21:54:30Z | |
dc.identifier.issn | 1548-9213 | |
dc.identifier.uri | http://hdl.handle.net/1885/38968 | |
dc.description.abstract | Absorption of amino acids in kidney and intestine involves a variety of transporters for different groups of amino acids. This is illustrated by inherited disorders of amino acid absorption, such as Hartnup disorder, cystinuria, iminoglycinuria, dicarboxylic aminoaciduria, and lysinuric protein intolerance, affecting separate groups of amino acids. Recent advances in the molecular identification of apical neutral amino acid transporters has shed a light on the molecular basis of Hartnup disorder and iminoglycinuria. | |
dc.publisher | American Physiological Society | |
dc.source | Physiology | |
dc.subject | Keywords: amino acid transporter; animal; chemistry; Hartnup disease; human; pathophysiology; physiology; protein conformation; review; structure activity relation; Amino Acid Transport Systems, Neutral; Animals; Hartnup Disease; Humans; Protein Conformation; Struc | |
dc.title | Apical Transporters for Neutral Amino acids: Physiology and Pathophysiology | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 23 | |
dc.date.issued | 2008 | |
local.identifier.absfor | 060110 - Receptors and Membrane Biology | |
local.identifier.ariespublication | u4325460xPUB169 | |
local.type.status | Published Version | |
local.contributor.affiliation | Broer, Stefan, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.startpage | 95 | |
local.bibliographicCitation.lastpage | 103 | |
local.identifier.doi | 10.1152/physiol.00045.2007 | |
dc.date.updated | 2015-12-09T07:26:42Z | |
local.identifier.scopusID | 2-s2.0-42049122112 | |
local.identifier.thomsonID | 000256685300005 | |
Collections | ANU Research Publications |
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