Ibister, Geoffrey K.; Friberg, Lena E.; Stokes, Barrie; Buckley, Nicholas; Lee, Christopher; Gunja, Naren; Brown, Simon G.; MacDonald, Ellen; Graudins, Andis; Holdgate, Anna; Duffull, Stephen B.
Study objective: We determine whether single-dose activated charcoal (SDAC) administration after citalopram overdose reduces the proportion of patients developing abnormal QT prolongation. Methods: Data were collected retrospectively for citalopram overdose patients presenting to 8 emergency departments. Demographics, dose, coingested drugs, SDAC administration, and serial ECGs were extracted from medical records. The primary outcome was the proportion of patients who had an observed QT,RR...[Show more]
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