Bystander protein protects potential vaccine-targeting ligands against intestinal proteolysis
Endowing mucosal vaccines with ligands that target antigen to mucosal lymphoid tissues may improve immunization efficacy provided that the ligands withstand the proteolytic environment of the gastro-intestinal tract until they reach their destination. Our aim was to investigate whether and how three renowned ligands - Ulex europaeus agglutinin I and the B subunits of cholera toxin and E. coli heat-labile enterotoxin - master this challenge. We assessed the digestive power of natural murine...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Controlled Release|
|01_Reuter_Bystander_protein_protects_2009.pdf||409.96 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.