Skip navigation
Skip navigation

Bystander protein protects potential vaccine-targeting ligands against intestinal proteolysis

Reuter, Fabian; Bade, Steffen; Hirst, Timothy; Frey, Andreas


Endowing mucosal vaccines with ligands that target antigen to mucosal lymphoid tissues may improve immunization efficacy provided that the ligands withstand the proteolytic environment of the gastro-intestinal tract until they reach their destination. Our aim was to investigate whether and how three renowned ligands - Ulex europaeus agglutinin I and the B subunits of cholera toxin and E. coli heat-labile enterotoxin - master this challenge. We assessed the digestive power of natural murine...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Journal of Controlled Release
DOI: 10.1016/j.jconrel.2009.03.015


File Description SizeFormat Image
01_Reuter_Bystander_protein_protects_2009.pdf409.96 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  22 January 2019/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator