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ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

Yabas, Mehmet; Teh, Charis; Frankenreiter, Sandra; Lal, Dennis; Roots, Carla; Whittle, Belinda; Andrews, Thomas Daniel; Zhang, Yafei; Teoh, Narcissus; Sprent, Jon; Tze, Lina; Kucharska, Edyta; Kofler, Jennifer; Farrell, Geoffrey; Broer, Stefan; Goodnow, Christopher; Enders, Anselm

Description

Subcompartments of the plasma membrane are believed to be critical for lymphocyte responses, but few genetic tools are available to test their function. Here we describe a previously unknown X-linked B cell-deficiency syndrome in mice caused by mutations

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/38103
Source: Nature Immunology
DOI: 10.1038/ni.2011

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