The Pto Kinase of Tomato, Which Regulates Plant Immunity,Is Repressed by Its Myristoylated N Terminus
Specific recognition of the Pseudomonas syringae effector proteins AvrPto and AvrPtoB in tomato is mediated by Pto kinase resulting in induction of defense responses, including hypersensitive cell death via a signaling pathway requiring the nucleotide-binding leucine-rich repeats protein Prf. Pto is amyristoylated protein, and N-myristoylation is required for signaling. Here we demonstrated a role for N-myristoylation in controlling Pto kinase activity. A myristoylated peptide corresponding to...[Show more]
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|Source:||Journal of Biological Chemistry|
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