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A Case-Sibling Assessment of the Association Between Skin Pigmentation and Other Vitamin D-related Factors and Type 1 Diabetes Mellitus

Ponsonby, Anne-Louise; Cameron, Fergus; Saffery, Richard; Pezic, Angela; Wong, Nick; Craig, Jeff; Ellis, Justine; Dwyer, Terence


Fair skin pigmentation has been associated with a higher risk of type 1 diabetes mellitus (T1DM). The aim is to compare children with T1DM directly to a sibling in relation to their skin pigmentation in sun-exposed and unexposed sites, past sun exposure and methylation of the VDR gene promoter. The sample consisted of children with T1DM attending a diabetes outpatient clinic and siblings (total n = 42). Cutaneous melanin density was estimated using a spectrophotometer. Parental report on past...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Photochemistry and Photobiology
DOI: 10.1111/j.1751-1097.2009.00563.x


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