The role of interchain heterodisulfide formation in activation of the human common β and mouse β IL-3 receptors
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Mirza, Shamaruh; Chen, Jinglong; Murphy, James M; Young, Ian
Description
The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony-stimulating factor (GM-CSF), exhibit overlapping activities in the regulation of hematopoietic cells. In humans, the common β (βc) receptor is shared by the thr
dc.contributor.author | Mirza, Shamaruh | |
---|---|---|
dc.contributor.author | Chen, Jinglong | |
dc.contributor.author | Murphy, James M | |
dc.contributor.author | Young, Ian | |
dc.date.accessioned | 2015-12-08T22:44:51Z | |
dc.identifier.issn | 0021-9258 | |
dc.identifier.uri | http://hdl.handle.net/1885/37582 | |
dc.description.abstract | The cytokines, interleukin-3 (IL-3), interleukin-5 (IL-5), and granulocyte-macrophage colony-stimulating factor (GM-CSF), exhibit overlapping activities in the regulation of hematopoietic cells. In humans, the common β (βc) receptor is shared by the thr | |
dc.publisher | American Society for Biochemistry and Molecular Biology Inc | |
dc.source | Journal of Biological Chemistry | |
dc.subject | Keywords: Binding epitopes; Cysteine residues; Cytokines; Granulocyte-macrophage colony-stimulating factors; Hematopoietic cell; High affinity binding; Interleukin-3; Interleukin-5; Isoforms; Ligand binding; Ligand-binding residues; N-terminal domains; N-terminals; | |
dc.title | The role of interchain heterodisulfide formation in activation of the human common β and mouse β IL-3 receptors | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 285 | |
dc.date.issued | 2010 | |
local.identifier.absfor | 060112 - Structural Biology (incl. Macromolecular Modelling) | |
local.identifier.ariespublication | f2965xPUB151 | |
local.type.status | Published Version | |
local.contributor.affiliation | Mirza, Shamaruh, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Chen, Jinglong, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Murphy, James M, The Walter and Eliza Hall Institute of Medical Research | |
local.contributor.affiliation | Young, Ian, College of Medicine, Biology and Environment, ANU | |
local.description.embargo | 2037-12-31 | |
local.bibliographicCitation.issue | 32 | |
local.bibliographicCitation.startpage | 24759 | |
local.bibliographicCitation.lastpage | 24768 | |
local.identifier.doi | 10.1074/jbc.M109.097881 | |
dc.date.updated | 2016-02-24T08:14:41Z | |
local.identifier.scopusID | 2-s2.0-77955282871 | |
local.identifier.thomsonID | 000280542100048 | |
Collections | ANU Research Publications |
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