Skip navigation
Skip navigation

Diversity in CD8 + T cell differentiation

Parish, Ian; Kaech, Susan

Description

CD8+ T cells are key effector cells of the adaptive immune system, however their activity must be tightly regulated to allow pathogen clearance whilst preventing immunopathology and autoimmunity. In this review, we summarise the diversity of responses that CD8+ T cells make to antigenic stimulation with a focus on how CD8+ T cell responses are regulated to achieve different immune outcomes. In particular, we discuss phenotypic diversity during tolerance induction as well as signals that drive...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/37321
Source: Current Opinion in Immunology
DOI: 10.1016/j.coi.2009.05.008

Download

File Description SizeFormat Image
01_Parish_Diversity_in_CD8_+__T_cell_2009.pdf533.08 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator