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Comparison of data analysis strategies for assessing treatment effectiveness in in pre-test-post-test designs with substantial dropout rates

Salim, Agus; Mackinnon, Andrew; Christensen, Helen; Griffiths, Kathleen


The pre-test-post-test design (PPD) is predominant in trials of psychotherapeutic treatments. Missing data due to withdrawals present an even bigger challenge in assessing treatment effectiveness under the PPD than under designs with more observations since dropout implies an absence of information about response to treatment. When confronted with missing data, often it is reasonable to assume that the mechanism underlying missingness is related to observed but not to unobserved outcomes...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Psychiatry Research
DOI: 10.1016/j.psychres.2007.08.005


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