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Dynamic histone variant exchange accompanies gene induction in T cells

Sutcliffe, Elissa; Parish, Ian; He, Yiqing; Juelich, Torsten; Tierney, Mary (Louise); Rangasamy, Danny; Milburn, Peter J; Tremethick, David; Rao, Sudha; Parish, Christopher


Changes in chromatin composition are often a prerequisite for gene induction. Nonallelic histone variants have recently emerged as key players in transcriptional control and chromatin modulation. While the changes in chromatin accessibility and histone posttranslational modification (PTM) distribution that accompany gene induction are well documented, the dynamics of histone variant exchange that parallel these events are still poorly defined. In this study, we have examined the changes in...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Molecular and Cellular Biology
DOI: 10.1128/MCB.01590-08


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