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Evidence that venoconstriction reverses the phase II sympathoinhibitory and brdaycardic response to haemorrhage

Potas, Jason; Dampney, Roger A L


Severe hypotensive haemorrhage results in a biphasic response, characterized by an initial increase in heart rate and sympathetic vasomotor activity (phase I) followed by a life-threatening hypotension, accompanied by profound sympathoinhibition and bradycardia (phase II). The phase II response is believed to be dependent on inputs from cardiopulmonary receptors, and may be triggered by the reduction in venous return and cardiac filling associated with severe haemorrhage. In this study, we...[Show more]

CollectionsANU Research Publications
Date published: 2004
Type: Journal article
Source: Autonomic Neuroscience: Basic and Clinical
DOI: 10.1016/j.autneu.2003.12.003


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