Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance
Parish, Ian; Waithman, Jason; Davey, Gayle M; Belz, Gabrielle; Mintern, Justine; Kurts, Christian; Sutherland, Robyn; Carbone, Francis; Heath, William R
Autoimmune diseases tend to be chronic and progressive, but how these responses are sustained is not clear. One cell type that might contribute to autoimmunity is the cytotoxic T lymphocyte (CTL), which, as a consequence of causing tissue destruction and
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