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Tissue destruction caused by cytotoxic T lymphocytes induces deletional tolerance

Parish, Ian; Waithman, Jason; Davey, Gayle M; Belz, Gabrielle; Mintern, Justine; Kurts, Christian; Sutherland, Robyn; Carbone, Francis; Heath, William R

Description

Autoimmune diseases tend to be chronic and progressive, but how these responses are sustained is not clear. One cell type that might contribute to autoimmunity is the cytotoxic T lymphocyte (CTL), which, as a consequence of causing tissue destruction and

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/37244
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.0810427106

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