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Involvement of DNA methylation in memory processing in the honey bee

Lockett, Gabrielle; Helliwell, Paul; Maleszka, Ryszard

Description

DNA methylation, an important and evolutionarily conserved epigenetic mechanism, is implicated in learning and memory processes in vertebrates, but its role in behaviour in invertebrates is unknown. We examined the role of DNA methylation in memory in the honey bee using an appetitive Pavlovian olfactory discrimination task, and by assessing the expression of DNA methyltransferase3, a key driver of epigenetic reprogramming. Here we report that DNA methyltransferase inhibition reduces...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/37192
Source: NeuroReport
DOI: 10.1097/WNR.0b013e32833ce5be

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