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Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells

Parish, Ian; Heath, William R

Description

Self-reactive T cells often escape thymic negative selection and are released into the periphery. While many of these T cells are tolerized by peripheral deletion or anergy, a proportion persists in a naïve (or ignorant) state. Self-ignorant T cells are

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/37164
Source: Immunology and Cell Biology
DOI: 10.1038/sj.icb.7100161

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