Classification of T cell movement tracks allows for prediction of cell function
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Kelemen, Reka K; He, GF; Woo, HL; Lane, T; Rempe, C; Wang, J; Cockburn, Ian; Amino, Rogerio; Ganusov, Vitaly V; Berry, MW
Description
Using a unique combination of visual, statistical, and data mining methods, we tested the hypothesis that an immune cell's movement pattern can convey key information about the cell's function, antigen specificity, and environment.We applied clustering, statistical tests, and a support vector machine (SVM) to assess our ability to classify different datasets of imaged flouresently labelled T cells in mouse liver.We additionally sawclusters of differentmovement patterns of T cells of identical...[Show more]
Collections | ANU Research Publications |
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Date published: | 2014 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/36794 |
Source: | International Journal of Computational Biology and Drug Design |
DOI: | 10.1504/IJCBDD.2014.06155 |
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01_Kelemen_Classification_of_T_cell_2014.pdf | 2.17 MB | Adobe PDF | Request a copy |
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