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Vitamin D status during pregnancy and aspects of offspring health

Ponsonby, Anne-Louise; Lewis, Sharon; Halliday, Jane; Lucas, Robyn

Description

Low maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored...[Show more]

dc.contributor.authorPonsonby, Anne-Louise
dc.contributor.authorLewis, Sharon
dc.contributor.authorHalliday, Jane
dc.contributor.authorLucas, Robyn
dc.date.accessioned2015-12-08T22:41:30Z
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/1885/36684
dc.description.abstractLow maternal vitamin D levels during pregnancy have been linked to various health outcomes in the offspring, ranging from periconceptional effects to diseases of adult onset. Maternal and infant cord 25(OH)D levels are highly correlated. Here, we review the available evidence for these adverse health effects. Most of the evidence has arisen from observational epidemiological studies, but randomized controlled trials are now underway. The evidence to date supports that women should be monitored and treated for vitamin D deficiency during pregnancy but optimal and upper limit serum 25(OH)D levels during pregnancy are not known.
dc.publisherMDPI Publishing
dc.sourceNutrients
dc.subjectKeywords: 25 hydroxyvitamin D; calcitriol; calcium; colecalciferol; immunoglobulin E; interleukin 10; parathyroid hormone; vitamin D; allergic disease; autoimmune disease; birth defect; birth weight; bone development; bone mineral; bone mineralization; brain tumor; Offspring health; Pregnancy; Sun exposure; Ultraviolet radiation; Vitamin D
dc.titleVitamin D status during pregnancy and aspects of offspring health
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume2
dc.date.issued2010
local.identifier.absfor111401 - Foetal Development and Medicine
local.identifier.ariespublicationu4637548xPUB139
local.type.statusPublished Version
local.contributor.affiliationPonsonby, Anne-Louise, Murdoch Children's Research Institute
local.contributor.affiliationLucas, Robyn, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationLewis, Sharon, Murdoch Childrens Research Institute
local.contributor.affiliationHalliday, Jane, Murdoch Childrens Research Institute
local.description.embargo2037-12-31
local.bibliographicCitation.issue3
local.bibliographicCitation.startpage389
local.bibliographicCitation.lastpage407
local.identifier.doi10.3390/nu2030389
dc.date.updated2016-02-24T11:16:15Z
local.identifier.scopusID2-s2.0-79952016038
local.identifier.thomsonID000298235100012
CollectionsANU Research Publications

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