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Acoustic attenuation compensation in photoacoustic tomography: Application to high-resolution 3D imaging of vascular networks in mice

Treeby, Bradley; Laufer, Jan G; Zhang, Edward Z; Norris, Francesca C; Lythgoe, Mark F; Beard, Paul C; Cox, Benjamin


The reconstruction algorithms commonly used in photoacoustic tomography do not account for the effects of acoustic attenuation on the measured time-domain signals. For experimental measurements made in biological tissue, acoustic attenuation causes the high frequency components of the generated ultrasound signals to be significantly reduced. When this signal loss is neglected, it manifests as a depth dependent magnitude error and blurring of features within the reconstructed photoacoustic...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Conference paper
Source: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
DOI: 10.1117/12.874530


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