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Biological pH sensing based on surface enhanced Raman scattering through a 2-aminothiophenol-silver probe

Wang, Zhuyuan; Bonoiu, Adela; Samoc, Marek; Cui, Yiping; Prasad, Paras N


We report pH sensing for biological applications based on surface enhanced Raman scattering (SERS) from silver nanoparticles functionalized with 2-aminothiophenol (2-aminobenzenethiol, 2-ABT). pH-dependent SERS spectra of the attached 2-ABT molecules enable one to sense the pH over the range of 3.0-8.0. We have performed the first demonstration of SERS detection in living cells kept in different pH buffer solutions and show that the pH sensitivity is retained in that case. Thus, the...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Biosensors and Bioelectronics
DOI: 10.1016/j.bios.2007.09.017


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