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IL-21 acts directly on B cells to regulate Bc1-6 expression and germinal center responses

Linterman, Michelle; Beaton, Laura; Yu, Di; Ramiscal, Roy; Srivastava, Monika; Hogan, Jennifer; Verma, Naresh; Smyth, Mark J; Rigby, Robert; Garcia De Vinuesa, Maria Carola

Description

During T cell-dependent responses, B cells can either differentiate extrafollicularly into short-lived plasma cells or enter follicles to form germinal centers (GCs). Interactions with T follicular helper (Tfh) cells are required for GC formation and for

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/36453
Source: Journal of Experimental Medicine
DOI: 10.1084/jem.20091738

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