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On the modelling of a bistable genetic switch

Santoso, Lucia; Lanzon, Alexander


A bistable switch is a common motif in a genetic regulatory network. There have been relatively few in vivo measurements made of such a network. Its natural closed loop nature makes the living switch difficult to measure experimentally. Hence not much have been reported on derivation of a model from in vivo data, which is expected to be different from the macroscopic scale in vitro measurements. We present a heuristic for modelling a naturally occurring switch from relatively few in vivo...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Conference paper
Source: Proceedings of the 45th IEEE Conference on Decision and Control


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