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The Modern Molecular Clock

Bromham, Lindell; Penny, David


The discovery of the molecular clock - a relatively constant rate of molecular evolution-provided an insight into the mechanisms of molecular evolution, and created one of the most useful new tools in biology. The unexpected constancy of rate was explained by assuming that most changes to genes are effectively neutral. Theory predicts several sources of variation in the rate of molecular evolution, However, even an approximate clock allows time estimates of events in evolutionary history, which...[Show more]

CollectionsANU Research Publications
Date published: 2003
Type: Journal article
Source: Nature Reviews: Genetics
DOI: 10.1038/nrg1020


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