Oseltamivir Ring Prophylaxis for Containment of 2009 H1N1 Influenza Outbreaks
Lee, Vernon; Yap, Jonathan; Cook, Alex R; Chen, Mark; Tay, Joshua K; Tan, Boon Huan; Loh, Jin Phang; Chew, Seok Wei; Koh, Wee Hong; Lin, Raymond T P; Cui, Lin; Lee, Charlie W.H; Sung, Wing-Kin; Wong, Christopher W.; Hibberd, Martin L.; Kang, Wee Lee; Seet, Benjamin; Tambyah, Paul A.
Background: From June 22 through June 25, 2009, four outbreaks of infection with the pandemic influenza A (H1N1) virus occurred in Singapore military camps. We report the efficacy of ring chemoprophylaxis (geographically targeted containment by means of prophylaxis) with oseltamivir to control outbreaks of 2009 H1N1 influenza in semiclosed environments. Methods: All personnel with suspected infection were tested and clinically isolated if infection was confirmed. In addition, we administered...[Show more]
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|Source:||New England Journal of Medicine|
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