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Mechanisms of Dexamethasone-Induced Hypertension

Ong, Sharon; Zhang, Yi; Whitworth, Judith


Hypertension is a well-recognized complication of excess glucocorticoids, both naturally-occurring and synthetic. Dexamethasone is a potent synthetic glucocorticoid, which has widespread clinical applications. As dexamethasone has purely glucocorticoid activity with negligible mineralocorticoid effects, dexamethasone-induced hypertension (DEX-HT) models have been used for studying the mechanisms of glucocorticoid-induced hypertension. This review examines the characteristics and mechanisms of...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Current Hypertension Reviews
DOI: 10.2174/157340209787314315


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