Tan, T H; Hemmings, Christine; Stafford-Bell, Martyn; Robson, Stephen; Goldstein, David; Yip, Desmond
To discuss the management of the uncommon situation of metastatic gastrointestinal tumour coexisting with pregnancy. We describe two cases of women with metastatic gastrointestinal stromal tumor (GIST) who successfully achieved a full-term pregnancy without complications and with the delivery of healthy infants. In both cases, treatment with imatinib mesylate was withheld during pregnancy because of its unknown effects and questionable safety for the developing fetus. The available data in the...[Show more]
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