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In vitro haematopoiesis of a novel dendritic-like cell present in murine spleen

Tan, Jonathan; O'Neill, Helen


Dendritic cells (DC) are important antigen presenting cells (APC) which induce and control the adaptive immune response. In spleen alone, multiple DC subsets can be distinguished by cell surface marker phenotype. Most of these have been shown to develop from progenitors in bone marrow and to seed lymphoid and tissue sites during development. This study advances in vitro methodology for haematopoiesis of dendritic-like cells from progenitors in spleen. Since spleen progenitors undergo...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Current Stem Cell Research & Therapy
DOI: 10.2174/157488810793351749


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