Skip navigation
Skip navigation

Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage

Poon, Ivan; Olsson, Anna-Karin; Hulett, Mark; Parish, Christopher

Description

The plasminogen/plasmin system is involved in a variety of normal physiological and pathological processes, including tissue remodelling, angiogenesis and tumour metastasis. Plasminogen activators and receptors for plasminogen/plasminogen activators are essential for the processing of plasminogen to form the active serine protease plasmin. Plasmin can in turn positively or negatively regulate further plasminogen activation via plasmin-mediated cleavage of receptors and activators. HRG...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/35017
Source: Biochemical Journal
DOI: 10.1042/BJ20090794

Download

File Description SizeFormat Image
01_Poon_Regulation_of_histidine-rich_2009.pdf1.06 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator