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Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters

Li, Rachel; Theriault, A G; Au, Karen; Douglas, Teresa D; Casaschi, A; Kurowska, Elzbieta M; Mukherjee, Rinee


The present study was undertaken to determine whether supplementation with polymethoxylated flavones (PMFs) could ameliorate the fructose-induced hypertriglyceridemia and other metabolic abnormalities associated with insulin resistance (IR) in hamsters. Following feeding with the fructose diet, hamsters were supplemented orally with PMF-L or PMF-H (62.5 and 125 mg/kg/day) for 4 weeks. Both PMF-treated groups showed a statistically significant (p < 0.05) decrease in serum triglyceride (TG) and...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: Life Sciences
DOI: 10.1016/j.lfs.2006.01.023


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