Glutathione Transferase P1: An Endogenous Inhibitor of Allergic Responses in a Mouse Model of Asthma
Rationale: Although epidemiological studies have linked asthma susceptibility and severity to polymorphisms in human glutathione transferase Pi (GSTP) 1, there is no direct evidence for a functional involvement of GSTP1 in processes that are pathognomic of asthma. Objectives: To examine the role of GSTP1 in modulating the development of allergic airways disease. Methods: Allergic airways disease was induced in wild-type (WT) and Gstp-null mice employing both acute and chronic models....[Show more]
|Collections||ANU Research Publications|
|Source:||American Journal of Respiratory and Critical Care Medicine|
|01_Zhou_Glutathione_Transferase_P1:_An_2008.pdf||906.11 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.