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Total and Regional Gray Matter Volume Is Not Related to APOE*E4 Status in a Community Sample of Middle-Aged Individuals

Cherbuin, Nicolas; Sachdev, Perminder Singh; Maller, Jerome; Meslin, Chantal; Mack, Holly; Wen, Wei; Easteal, Simon; Anstey, Kaarin

Description

Background. The APOE*E4 allele has been associated with greater gray matter atrophy and with Alzheimer's disease. The aim of this study was to investigate whether the relationship between cerebral gray matter atrophy and APOE*E4 genotype was also present

dc.contributor.authorCherbuin, Nicolas
dc.contributor.authorSachdev, Perminder Singh
dc.contributor.authorMaller, Jerome
dc.contributor.authorMeslin, Chantal
dc.contributor.authorMack, Holly
dc.contributor.authorWen, Wei
dc.contributor.authorEasteal, Simon
dc.contributor.authorAnstey, Kaarin
dc.date.accessioned2015-12-08T22:33:16Z
dc.date.available2015-12-08T22:33:16Z
dc.identifier.issn1079-5006
dc.identifier.urihttp://hdl.handle.net/1885/34606
dc.description.abstractBackground. The APOE*E4 allele has been associated with greater gray matter atrophy and with Alzheimer's disease. The aim of this study was to investigate whether the relationship between cerebral gray matter atrophy and APOE*E4 genotype was also present
dc.publisherOxford University Press
dc.sourceJournals of Gerontology Series A: Biological Sciences and Medical Sciences
dc.subjectKeywords: apolipoprotein E4; adult; allele; amygdaloid nucleus; article; brain atrophy; brain region; brain size; community sample; controlled study; female; gene frequency; genotype; gray matter; heterozygote; hippocampus; human; male; morphometrics; nuclear magne Amygdala; APOE; Cerebral atrophy; Hippocampus; MRI; Voxel-based morphometry
dc.titleTotal and Regional Gray Matter Volume Is Not Related to APOE*E4 Status in a Community Sample of Middle-Aged Individuals
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume63
dc.date.issued2008
local.identifier.absfor170100 - PSYCHOLOGY
local.identifier.ariespublicationu4020362xPUB115
local.type.statusPublished Version
local.contributor.affiliationCherbuin, Nicolas, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationAnstey, Kaarin, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationSachdev, Perminder Singh, University of New South Wales (Prince of Wales Hospital)
local.contributor.affiliationMaller, Jerome, Alfred Hospital
local.contributor.affiliationMeslin, Chantal, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMack, Holly, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationWen, Wei, University of New South Wales (Prince of Wales Hospital)
local.contributor.affiliationEasteal, Simon, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue5
local.bibliographicCitation.startpage501
local.bibliographicCitation.lastpage504
dc.date.updated2015-12-08T09:34:20Z
local.identifier.scopusID2-s2.0-47049087411
CollectionsANU Research Publications

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