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Activation of cathepsin D by glycosaminoglycans

Beckman, Marie; Freeman, Craig; Small, David H; Parish, Christopher

Description

We have previously shown that heparin can increase the activity of the proenzyme form of Alzheimer's β-site amyloid precursor protein cleaving enzyme 1 (BACE1). Cathepsin D (CD) is a member of the aspartic protease family and has sequence similarity to B

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/34484
Source: The FEBS Journal
DOI: 10.1111/j.1742-4658.2009.07444.x

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