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Sex differences in the causes and consequences of white matter hyperintensities

Sachdev, Perminder Singh; Parslow, Ruth; Wen, Wei; Anstey, Kaarin; Easteal, Simon


Objective: To examine sex differences in white matter hyperintensities (WMHs) on T2-weighted magnetic resonance imaging (MRI), reported to be more severe in older women. Methods: A random community sample of 228 men and 204 women, aged 60-64, underwent brain MRI scans. WMHs on T2-weighted FLAIR MRI scans were measured using an automated procedure. Subjects were assessed for physical health, cognitive function, vascular risk factors and Apolipoprotein E (APOE) genotyping. Results: Women had more...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Neurobiology of Aging
DOI: 10.1016/j.neurobiolaging.2007.08.023


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