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Uterine eosinophils and reproductive performance in interleukin 5-deficient mice.

Robertson, S; Mau, V; Young, I M; Matthaei, Klaus


Interleukin 5 is expressed in type 2 T lymphocytes and has a key role in driving the differentiation, recruitment and activation of eosinophils. Mice with a null mutation in the interleukin 5 gene (IL-5 -/- mice) have altered type 2 immune responses and severely depleted eosinophil populations. In the present study, the effect of interleukin 5 deficiency on the abundant population of eosinophils present in the female reproductive tract was investigated, and the reproductive performance in...[Show more]

CollectionsANU Research Publications
Date published: 2000
Type: Journal article
Source: Journal of Reproduction and Fertility


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