T cell receptor sharing by cytotoxic T lymphocytes facilitates efficient virus control
A remarkable feature of the adaptive immune system is the speed at which small numbers of antigen-specific lymphocytes can mediate a successful immune response. Rapid expansion of T and B lymphocyte clones that have receptors specific for a particular antigen is one of the primary means by which a swift response is generated. Although much of this clonal expansion is caused by the division of antigen-specific cells, herewedemonstrate an additional mechanism by which the pool of effector T cells...[Show more]
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|Source:||PNAS - Proceedings of the National Academy of Sciences of the United States of America|
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