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The IL-3/IL-5/GM-CSF common receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammation

Asquith, Kelly L; Ramshaw, Hayley S; Hansbro, Phil M; Beagley, Kenneth W; Lopez, Angel F; Foster, Paul S


The eosinophil is a central effector cell in allergic asthma. Differentiation and function of eosinophils are regulated by the CD4 Th2 cytokines IL-3, IL-5, and GM-CSF, which all signal through a common β receptor subunit (βc). Recent therapeutic approa

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Immunology


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