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Efflux of a range of antimalarial drugs and 'chloroquine resistance reversers' from the digestive vacuole in malaria parasites with mutant PfCRT

Lehane, Adele; Kirk, Kiaran


Chloroquine-resistant malaria parasites (Plasmodium falciparum) show an increased leak of H+ ions from their internal digestive vacuole in the presence of chloroquine. This phenomenon has been attributed to the transport of chloroquine, together with H+,

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Molecular Microbiology
DOI: 10.1111/j.1365-2958.2010.07272.x


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