Skip navigation
Skip navigation

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy

Ellis, Leigh; Bots, Michael; Lindemann, Ralph K.; Bolden, Jessica E.; Newbold, Andrea; Cluse, Leonie A.; Scott, Clare L.; Strasser, Andreas; Atadja, Peter; Lowe, Scott W.; Johnstone, Ricky


LAQ824 and LBH589 (panobinostat) are histone deacetylase inhibitors (HDACi) developed as cancer therapeutics and we have used the Eμ-myc lymphoma model to identify the molecular events required for their antitumor effects. Induction of tumor cell death w

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Blood
DOI: 10.1182/blood-2008-10-182758


File Description SizeFormat Image
01_Ellis_The_histone_deacetylase_2009.pdf2.99 MBAdobe PDFThumbnail

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator