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Hormone replacement therapy and incidence of central nervous system tumours in the Million Women Study

Benson, Victoria S; Pirie, Kirstin; Green, Jane; Bull, Diana; Casabonne, Delphine; Reeves, Gillian K; Beral, Valerie; Banks, Emily; Million Women Study, Collaborators


We examined the relation between the use of hormone replacement therapy (HRT) and the incidence of central nervous system (CNS) tumours in a large prospective study of 1,147,894 postmenopausal women. Women were aged 56.6 years on average at entry, and HRT use was recorded at recruitment and updated, where possible, about 3 years later. During a mean follow-up of 5.3 years per woman, 1,266 CNS tumours were diagnosed, including 557 gliomas, 311 meningiomas and 117 acoustic neuromas. Compared with...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: International Journal of Cancer
DOI: 10.1002/ijc.25184


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