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Protective CD8+ T cells against Plasmodium liver stages: immunobiology of an 'unnatural' immune response

Overstreet, Michael G; Cockburn, Ian; Zavala, Fidel

Description

Immunization with high doses of irradiated sporozoites delivered by the bites of infected mosquitoes has been shown to induce protective responses against malaria, mediated in part by CD8+ T cells. In contrast, natural transmission involving low exposure

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/33681
Source: Immunological Reviews
DOI: 10.1111/j.1600-065X.2008.00671.x.Review

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