Proliferation markers and survival in early breast cancer
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Stuart-Harris, Robin; Caldas, C; Pinder, S; Pharoah, P
Description
We have performed a systematic review and meta-analysis of proliferation markers (Ki-67, mitotic index (MI), proliferating cell nuclear antigen (PCNA) and thymidine or bromodeoxyuridine labelling index (LI)) with respect to survival in early breast cancer. Eighty-five studies involving 32,825 patients were analysed. Ki-67 (43 studies, 15,790 patients), MI (20 studies, 7021 patients), and LI (11 studies, 7337 patients) were associated with significantly shorter overall and disease free survival,...[Show more]
Collections | ANU Research Publications |
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Date published: | 2008 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/33623 |
Source: | The Breast |
DOI: | 10.1016/j.breast.2008.02.002 |
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File | Description | Size | Format | Image |
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01_Stuart-Harris_Proliferation_markers_and_2008.pdf | 336.63 kB | Adobe PDF | Request a copy |
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