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B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

Joshi, Trupti; Rodriguez, Susana; Perovic, Vladimir; Cockburn, Ian; Stager, Simona

Description

Experimental visceral leishmaniasis (VL) represents an exquisite model to study CD8+ T cell responses in a context of chronic inflammation and antigen persistence, since it is characterized by chronic infection in the spleen and CD8+ T cells are required

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/33586
Source: PLoS Pathogens
DOI: 10.1371/journal.ppat.1000431

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